When 250 ml runs out faster than expected
DMSO Dimethyl Sulfoxide in pharmaceutical-grade purity (Ph. Eur. 8.0) — this 500 ml fill is the natural step up once usage becomes routine.
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99.99 % content (Ph. Eur.)
Verified purity to the European Pharmacopoeia. With larger bottles the specification has to hold all the way to the last drop — that is the entire promise of pharmaceutical grade.
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Polar aprotic solvent
High solvating power, fully miscible with water. During freezing DMSO prevents the formation of ice crystals — well established in research and analytics.
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Vegan & REACH-registered
Synthetically produced from non-animal starting materials. Registered under Regulation (EC) 1907/2006, country of origin France.
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500 ml brown glass + pipette
Half a litre of pharmaceutical-grade purity in amber apothecary glass. Plastic pipette included for clean withdrawal.
The smaller bottles work well as a starting point — but anyone using DMSO regularly knows the pattern: one bottle in the cabinet, another already opened, a third just ordered. At some point the larger pack size simply becomes the more practical option.
This 500 ml fill delivers pharmaceutical-grade dimethyl sulfoxide (CAS 67-68-5) with a molar mass of 78.13 g/mol and a density of 1.104 g/cm³ at 20 °C. The documented content is 99.99 %, verified to Ph. Eur. 8.0. The melting point of around 18 °C is independent of bottle size — even at half a litre the substance crystallises at cool temperatures. Pure physics.
Behind this fill sits the same documentation as the smaller bottles: certificate of analysis to Ph. Eur. 8.0, safety data sheet under Regulation (EC) 1907/2006 and a REACH registration. All starting materials are of non-animal origin. If you would like to explore further options from the Viterna range, you may also wish to take a look at Vital Eyebright Drops 100 ml and the Vital Artemisia DMSO Tincture (alcohol-free) 100 ml.
📊 500 ml DMSO 99.9 % at a glance
99.99 %
Content per Ph. Eur.
1.104 g/cm³
Density (20 °C)
📋 Handling notes
DMSO serves as a carrier substance, a so-called transport mediator and a general solvent. During freezing processes it prevents the formation of ice crystals in the frozen material.
Manufacturer-declared uses: laboratory chemical · solvent · chemical analytics · chemical for various applications · manufacture of substances.
Please note that handling chemicals always requires care and caution.
Chemical and physical specifications
| Specification |
Value |
| Content |
99.99 % (Ph. Eur. 8.0) |
| Molecular formula |
C₂H₆OS |
| Molar mass |
78.13 g/mol |
| Density (20 °C) |
1.104 g/cm³ |
| Melting point |
18.2 °C |
| Refractive index |
1.479 |
| Water content (K.F.) |
< 0.2 % |
| Related substances |
< 0.1 % |
| CAS number |
67-68-5 |
| EC number |
200-664-3 |
| Storage class |
10-13 |
| Country of origin |
France (EU) |
Trade name: DMSO Dimethyl Sulfoxide 99.9 % – pharmaceutical-grade purity to the European Pharmacopoeia (Ph. Eur. 8.0)
Composition: Dimethyl sulfoxide (≥ 99.99 % to Ph. Eur.), free from materials of animal origin
Net quantity: 500 ml
Packaging: Amber glass bottle with original closure, plastic pipette included
REACH registration number: 01-2119431362-50-XXXX
Pharmaceutical grade vs. technical grade — where is the difference?
Technical DMSO meets the requirements for industrial applications but does not specify accompanying substances, water content or identity verification. Ph. Eur. quality sits a step higher: documented minimum purity, defined ceilings for impurities (related substances < 0.1 %), water content < 0.2 % and a full identity check according to the European Pharmacopoeia methods A–D.
Which pack sizes are available?
Alongside this 500 ml variant, there are also 250 ml for getting started and 1000 ml for higher demand — all in the same pharmaceutical quality.
⚠️ Pharmaceutical-grade (Ph. Eur.): Please note that handling chemicals always requires care and caution. DMSO freezes at temperatures below 18 °C. This is not a defect, but a physical property. Always store in warm conditions and re-liquefy crystallised material by gentle warming. Keep out of reach of children.
📦 Storage: Store upright. At low temperatures DMSO can crystallise – the ideal storage range is approximately 20–22 °C. Protect from light.
💬 Frequently asked questions
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Why has my DMSO crystallised?+
The melting point of dimethyl sulfoxide sits at around 18 °C. At cooler temperatures the substance solidifies — with the 500 ml bottle re-liquefying takes correspondingly longer than with smaller fills. A water bath at 25–30 °C brings it back into the liquid state without any loss of purity.
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What does "Ph. Eur. 8.0" mean?+
"Ph. Eur." stands for "Pharmacopoea Europaea" — the official European pharmaceutical reference work that sets binding quality and purity requirements for pharmaceutically used substances. The "8.0" indicates the edition of the pharmacopoeia against which the material was tested.
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How long does DMSO remain usable after opening?+
DMSO is chemically very stable. With the bottle tightly sealed, stored away from light and at room temperature, the material remains unchanged for a long time. DMSO is hygroscopic — so the bottle should be resealed promptly after every withdrawal to avoid moisture uptake from ambient air.
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Is this DMSO vegan?+
DMSO is produced synthetically. In the current certificate of analysis the manufacturer guarantees that the starting materials used are of non-animal origin.
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Why an amber glass bottle?+
Amber glass filters out short-wavelength light and is the classic apothecary container for light-sensitive substances. Particularly with larger fills that are often stored for longer periods, the light protection is a practical advantage.
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How should DMSO be stored?+
Upright, protected from light, at room temperature between roughly 20 and 22 °C. Cooler conditions will cause the liquid to solidify, but no harm is done. Keep out of reach of children.
Responsible Person (GPSR, EU 2023/988) & operator placing on the market: vitalundfitmit100 GmbH · Siemensstraße 10 · D-41363 Jüchen · Germany · info@vitalundfitmit100.de · Manufactured in France.
